Effect of spacer sequences between bla CTX-M and ISEcp1 on bla CTX-M expression
نویسندگان
چکیده
منابع مشابه
High prevalence of bla(CTX-M) extended spectrum beta-lactamase genes in Klebsiella pneumoniae isolates from a tertiary care hospital: first report of bla(SHV-12), bla(SHV-31), bla(SHV-38), and bla(CTX-M-15) in Brazil.
The aim of this study was to investigate the presence and prevalence of bla(TEM), bla(SHV), and bla(CTX-M) and bla(GES)-like genes, responsible for extended spectrum beta-lactamases (ESBLs) production in clinical isolates of Klebsiella pneumoniae collected from a Brazilian tertiary care hospital. Sixty-five ESBL producing K. pneumoniae isolates, collected between 2005 and 2007, were screened by...
متن کاملbla(CTX-M-2) and bla(CTX-M-28) extended-spectrum beta-lactamase genes and class 1 integrons in clinical isolates of Klebsiella pneumoniae from Brazil.
Twenty-eight Klebsiella pneumoniae clinical isolates that exhibited an extended-spectrum cephalosporin-resistance profile from a city in the Northeast of Brazil were analysed by PCR and DNA sequencing in order to determine the occurrence of blaCTX-M genes and class 1 integrons. We determined the occurrence of the blaCTX-M-2 gene in six K. pneumoniae isolates and describe the first detection of ...
متن کاملMultiplex PCR for bla(CTX-M) & bla(SHV) in the extended spectrum beta lactamase (ESBL) producing gram-negative isolates.
BACKGROUND & OBJECTIVE Phenotyping is commonly used for detection of extended spectrum beta lactamase (ESBL) production in gram-negative isolates. ESBLs are mainly coded for by three important genes, namely bla(TEM), bla(SHV) and bla(CTX-M). In this study we used a multiplex PCR as a rapid method to identify two common genes (bla(CTX-M) & bla(SHV)) responsible for extended spectrum beta lactama...
متن کاملSpread of bla(CTX-M-type) and bla(PER-2) beta-lactamase genes in clinical isolates from Bolivian hospitals.
OBJECTIVES To assess the prevalence and types of genes encoding extended-spectrum beta-lactamases (ESBLs) in clinical isolates of Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp. from Bolivia. METHODS A total of 642 clinical isolates were collected consecutively during a 4 month period (September to December 2004). Resistance or reduced susceptibility to cefotaxime and/or cef...
متن کاملارزیابی ژن bla-ctx-m-type در سویه‌های کلبسیلاپنومونیه چند مقاومتی جدا شده از نمونه‌های کلینیکی
Background and Aim: Klebsiella pneumoniae (K. Pneumoniae) is one of the prevalent infectious bacteria, especially in hospitalized patients. Recently, its' multi drug resistance (MDR) trait has become more important and regarded as a virulant factor. In this study, we evaluated bla-ctx-m-type gene in clinical isolates of K.pneumoniae with multi drug resistance. Materials and Methods: In this d...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2011
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.033910-0